GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| BLCA | cis | rs9783347 | 1 | rs4150612 | chr11:18364358 | GTF2H1 | chr11:18343816-18388590:+ | 0.31 | 5.88 | 8.76E-9 | Pancreatic cancer |
| BLCA | cis | rs9783347 | 1 | rs4150615 | chr11:18365028 | GTF2H1 | chr11:18343816-18388590:+ | -0.29 | -5.36 | 1.47E-7 | Pancreatic cancer |
| BLCA | cis | rs9783347 | 1 | rs4150622 | chr11:18365710 | GTF2H1 | chr11:18343816-18388590:+ | 0.31 | 6.01 | 4.36E-9 | Pancreatic cancer |
| BLCA | cis | rs9783347 | 1 | rs4150641 | chr11:18370739 | GTF2H1 | chr11:18343816-18388590:+ | 0.31 | 6 | 4.6E-9 | Pancreatic cancer |
| BLCA | cis | rs9783347 | 1 | rs4150650 | chr11:18374279 | GTF2H1 | chr11:18343816-18388590:+ | 0.31 | 6.04 | 3.75E-9 | Pancreatic cancer |
| BLCA | cis | rs9783347 | 1 | rs4150651 | chr11:18374425 | GTF2H1 | chr11:18343816-18388590:+ | 0.31 | 6.04 | 3.75E-9 | Pancreatic cancer |
| BLCA | cis | rs9783347 | 1 | rs4150655 | chr11:18375164 | GTF2H1 | chr11:18343816-18388590:+ | -0.28 | -5.4 | 1.16E-7 | Pancreatic cancer |
| BLCA | cis | rs9783347 | 1 | rs4150661 | chr11:18379629 | GTF2H1 | chr11:18343816-18388590:+ | 0.29 | 5.52 | 6.15E-8 | Pancreatic cancer |
| BLCA | cis | rs9783347 | 1 | rs4150673 | chr11:18383449 | GTF2H1 | chr11:18343816-18388590:+ | 0.29 | 5.39 | 1.24E-7 | Pancreatic cancer |
| BLCA | cis | rs9457247 | 1 | rs415842 | chr6:167406681 | RNASET2 | chr6:167343008-167412795:- | -0.25 | -5.16 | 4.07E-7 | Crohn's disease |
| BLCA | cis | rs9457247 | 1 | rs415890 | chr6:167406633 | RNASET2 | chr6:167343008-167412795:- | 0.25 | 5.21 | 3.07E-7 | Crohn's disease |
| BLCA | cis | rs9457247 | 1 | rs416131 | chr6:167406544 | RNASET2 | chr6:167343008-167412795:- | 0.23 | 4.89 | 1.52E-6 | Crohn's disease |
| BLCA | cis | rs2243480 | 1 | rs419603 | chr7:65597341 | CCT6P1 | chr7:65216092-65228661:+ | 0.33 | 4.56 | 6.79E-6 | Diabetic kidney disease |
| BLCA | cis | rs420259 | 1 | rs420259 | chr16:23634026 | EARS2 | chr16:23533335-23568696:- | 0.25 | 3.97 | 8.42E-5 | Bipolar disorder |
| BLCA | cis | rs9457247 | 1 | rs421214 | chr6:167396629 | RNASET2 | chr6:167343008-167412795:- | -0.24 | -5.08 | 5.88E-7 | Crohn's disease |